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Seattle Children's Hospital Postdoctoral Fellow - PhD (Parish Lab) in Seattle, Washington

TB remains a serious global health problem and there is an urgent need for new therapeutic agents. The Parish Lab (https://www.linkedin.com/in/tanya-parish-a564056/) is looking for a post-doctoral scientist to work on a tuberculosis drug discovery project. The successful candidate will work in a multi-disciplinary research environment, interacting with chemists and microbiologists on multiple projects. The candidate will work on a research project to develop novel inhibitors of respiration in the global human pathogen Mycobacterium tuberculosis; they will also conduct research into mode of action of new inhibitors.

Description of Responsibilities:

• Conduct a research and development project

• Design and implement research plans

• Troubleshoot and solve experimental and technical problems

• Prepare and present papers, reports, and presentations of current research work

• Write manuscripts and assist with grant preparation

• Oversee quality control and data integrity

• May supervise one or more research assistants

Specific duties include:

• Work under Biosafety Level 3 conditions with Mycobacterium tuberculosis

• Characterization and development of small molecules as candidate anti-tubercular agents using a wide range of microbiological and cellular assays.

• Determine mechanism of kill and resistance mechanisms for new anti-tubercular agents targeting respiration.

• Conduct in vitro drug combination studies with new anti-tubercular agents.

Required Education/Experience:

  • PhD in specialty area from an accredited university training program

  • Experience using basic research techniques of specialty area

Preferred:

  • Previous experience conducting research in the pediatric arena

  • Experience in protocol and manuscript development and in grant writing

External Job Title: Postdoctoral Fellow - PhD (Parish Lab)

Job ID / Requisition Number: 2020-35389

FTE/Hours per pay period: 1.0 FTE (80 hours per bi-weekly pay periods)

Name: Global Infectious Disease

Shift: Day Shift

Street: 307 Westlake Ave N

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