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Arrowhead Pharmaceuticals Associate Chemist, Small Scale Synthesis in Madison, Wisconsin

The Position

Arrowhead Pharmaceuticals is seeking an Associate Chemist to join the Discovery Chemistry Department. The successful candidate will primarily focus on oligonucleotide synthesis, purification, analytical chemistry, and contributing to specific program goals. S/He will be joining a team of highly motivated and experienced scientists and will contribute to the success of Arrowhead programs.


  • Maintain a well-documented laboratory notebook

  • Track progress against project timelines, generate regular status updates, and communicate progress and issues to management

  • Perform tasks across projects

  • Manage time effectively to meet deadlines

  • Adhere to safe laboratory practices

  • Perform synthesis, purification, and analysis of oligonucleotides

  • Assist with maintenance of bioconjugate and oligonucleotide inventory


  • B.S. Chemistry or Biochemistry degree with excellent understanding of organic and analytical chemistry

  • 0-2 years of experience working in a chemistry laboratory

  • Experience with a wide range of analytical techniques, especially HPLC

  • Ability to quickly learn new procedures and techniques


  • Experience working with large molecule synthetic targets (especially oligonucleotides) either in an academic or industry setting

  • Previous experience working in pharmaceutical setting

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