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Alexion Pharmaceuticals Senior Manager, Commercial IT in Boston, Massachusetts

The Alexion IT organization is looking for a Sr. Manager, Commercial IT to join their US Commercial IT (Go-to- Market team). This role is a business partner role for the US Commercial Organization in maintaining the Commercial relationships and projects that align to key business priorities. In addition, the Sr. Manager will be responsible for maintaining the portfolio of projects and initiatives across the Commercial IT team and business demand. She/he is responsible to coordinate and lead the business process design and implementation of technology solutions with the IT Service Delivery Team aligned to the System Delivery Life Cycle (SDLC) process. Additionally, the Sr Manager will be responsible for producing monthly and ad-hoc reports providing insight into the team’s portfolio. The individual must be a self-starter with strong communication, organizational, and influencing skills who will work to become a trusted partner within the Commercial organization and across IT.

The Senior Manager, Commercial IT is a key member of the Commercial IT Team reporting to Senior Director of IT US Commercial & Medical (Go-to-Market Team) and is responsible for the US region. She/he will work closely with the regional IT Business partners and Marketing IT Business Partners to drive alignment of the portfolio.


  • Partner with US Commercial IT’s Business partners to understand business demand that will drive solutions to contribute to success of Alexion’s business

  • Manage select project assigned and work closely as a trusted business partner to execute these projects.

  • Partner with US Commercial IT Business partners to ensure the projects are included within the portfolio and tracked appropriately

  • Understand and translate business requirements to functional requirements for commercial objectives

  • Work with the US Commercial IT Business partners do develop therapeutic specific roadmaps and portfolio(s)

  • Partner with the Commercial Business Operations teams to ensure alignment

  • Coordinate and lead the business process design and implementation of technology solutions with IT Enterprise Application team, the Digital team & Service Delivery Team

  • Spearhead projects to identify process improvements for business processes

  • Help to create and implement processes to ensure seamless ongoing support for commercial solutions at all levels

  • Work closely with the business on the documentation of business processes

  • Create required SDLC documentation like Business Case, User Requirements specification, UAT plan, etc.

  • Understand business initiatives to ensure compliance in all systems

  • Partner with systems administrator/developer to develop requirements and prepare development specifications

  • Lead development and execution of test scripts as required by corporate change control and SDLC guidelines

  • Perform other function-related activities in addition to the above mentioned responsibilities as reasonably required by business needs

  • This position can be based remote/virtual and may require up to 20% travel

Essential Qualifications

  • Minimum 10 years of IT experience in functional areas and exposure to business operations managing IT portfolios

  • Project management experience required; development and support of complex projects and solutions

  • Strong experience in CRM and/or experience required

  • Understanding of marketing and digital technologies; hands on experience a plus

  • Experience working in a multi-disciplined, multi-functional matrix organization

  • Experience working in Biotech or Pharmaceutical industry

  • Understanding of SDLC guidelines

  • Understanding of corporate compliance and government regulations


  • Bachelors degree in Computer Science, MIS or a related field.

  • MBA is a plus

This position can be based from the Alexion location of Boston, MA, or can be remote/virtual, based anywhere in the United Staes and may require up to 20% travel.


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Some opportunities happen only once in a lifetime - like a job where you have the extraordinary opportunity to change lives. At Alexion, such opportunities arise through our unwavering mission to serve patients and families affected by rare diseases. These patients are our guiding star, and we act with integrity, urgency, and discipline because we know their lives are at stake.

Alexion is a global biopharmaceutical company focused on serving patients and families affected by rare diseases and devastating conditions through the discovery, development and commercialization of life-changing medicines. As a leader in rare diseases for more than 25 years, Alexion has developed and commercializes two approved complement inhibitors to treat patients with paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic syndrome (aHUS), as well as the first and only approved complement inhibitor to treat anti-acetylcholine receptor (AchR) antibody-positive generalized myasthenia gravis (gMG) and neuromyelitis optica spectrum disorder (NMOSD). Alexion also has two highly innovative enzyme replacement therapies for patients with life-threatening and ultra-rare metabolic disorders, hypophosphatasia (HPP) and lysosomal acid lipase deficiency (LAL-D) as well as the first and only approved Factor Xa inhibitor reversal agent. In addition, the company is developing several mid-to-late-stage therapies, including a copper-binding agent for Wilson disease, an anti-neonatal Fc receptor (FcRn) antibody for rare Immunoglobulin G (IgG)-mediated diseases and an oral Factor D inhibitor as well as several early-stage therapies, including one for light chain (AL) amyloidosis, a second oral Factor D inhibitor and a third complement inhibitor. Alexion focuses its research efforts on novel molecules and targets in the complement cascade and its development efforts on the core therapeutic areas of hematology, nephrology, neurology, metabolic disorders and cardiology. Headquartered in Boston, Massachusetts, Alexion has offices around the globe and serves patients in more than 50 countries. Further information about Alexion can be found at:

As a leading employer in our industry, Alexion is proud to offer a highly competitive package of base and incentive compensation as well as a comprehensive benefits program designed to support the health, wellness and financial security of our employees and their families. Benefits include group medical, vision and dental coverage, group and supplemental life insurance, 401(k) with company match, tuition reimbursement, relocation assistance and much more.