Genomic Expression Inc Senior Bioinformatics Role at Cancer Diagnostics Company in boston, Massachusetts
Genomic Expression is seeking a senior-level bioinformatician to run our bioinformatics operations and lead further development of our OneRNA platform. This person must be skilled in all facets of bioinformatics analysis, and possess deep expertise in analysis of tumor RNA and DNA sequencing data. You will be working alongside pioneers in oncology, bench scientists, engineers, and software developers to develop new cancer diagnostic tests and better match cancer patients to treatment options.
Responsibilities and Duties
Develop novel methods to analyze and interpret tumor sequencing data in a clinical context
Create and optimize new bioinformatics pipelines
Perform analysis of experimental data sets and present results to the lab team
Work with external collaborators to design and interpret cancer research studies
Supervise routine operation of our sequencing bioinformatic analysis pipeline
Monitor sequencing data quality and work with lab team to address deviations
Represent bioinformatics needs in company planning related to IT infrastructure
Create weekly, quarterly and longer term plans related to genomic data analysis and infrastructure
Supervise writing of data-related protocols and SOPs
Hire and manage and mentor junior bioinformatics staff
Hire and manage external contractors working for data-related projects
Qualifications, Skills and Expertise:
PhD in Bioinformatics, Computational Biology or Biological Sciences with strong quantitative background involving the analysis of next generation sequencing data (including RNA sequencing data), or Master?s degree with equivalent research experience
Experience working in both academia and industry
Demonstrated ability to innovate and solve challenging problems
Deep knowledge of genomics, bioinformatics, biostatistics and cancer biology
Experience in development, selection, validation an operation of tools and open source software related to data analysis such as gene expression, pathway identification, variant calling, copy number variation identification, structural variants identification, gene fusion, allele specific gene expression, novel transcripts, etc.
Experience in interpreting data derived from NGS sequencing in the context of cancer research
Ability to lead interdisciplinary teams to plan experiments and interpret resulting data
Demonstrated ability to supervise and mentor less experienced data scientists, including entry level staff and students
Excellent written and verbal communication skills
Experience developing scripts for processing NGS data in languages that include Python and R
Experience with cloud computing platforms such as AWS
Understanding or willingness to understand regulatory environments such as HIPAA and CLIA
MUST BE PREPARED TO ADOPT AN ENGINEERING MINDSET: BUILD, TEST, DEPLOY, REPEAT
At Genomic Expression, we are building a company to address the urgent need for better cancer treatments. Currently only 1 out of 4 cancer treatment prolongs life, yet we spend $100 billion on drugs and 8 million patients die every year from the disease. Genomic Expression is changing this paradigm by sequencing tumor RNA to find the best drug for the patient, and the best patient for the drug. With four funded programs in various cancer types, including breast and ovarian cancer, Genomic Expression is a first mover in making RNA sequencing actionable in oncology.
? 1 min Product Video: http://bit.ly/OneRNAMovie? 1 min Company video: http://bit.ly/GExCorp? Website: http://www.genomicexpression.com/? Twitter: @dnabarcode (+ 50,000 followers)
Company DNA:Our company culture is based on respect for the individual and admiration for creativity and intellect. We will honor anybody?s ability to create value for our company. We are team oriented and expect our employees to take responsibility and initiative.
We are prioritizing candidates from the greater Boston area. This position will be located at Genomic Expression's headquarters in Beverly, Massachusetts about 40 minutes north of Boston.
You will work with an entrepreneurial team that offers significant growth opportunities and the opportunity to improve the care of cancer patients. Company benefits include paid vacation and employee stock options.